Hengameh Jannati - Department of biology, Science and Research branch, Islamic Azad University, Tehran, Iran.
Seyed Davar Siadat - Department of Mycobacteriology and Pulmonary Research, Pasteur institute of Iran, Tehran, Iran. Microbiology Research Center (MRC), Pasteur institute of Iran, Tehran, Iran
Parvaneh Safarian - Department of biology, Science and Research branch, Islamic Azad University, Tehran, Iran.
Mojgan Sheikhpour - Department of Mycobacteriology and Pulmonary Research, Pasteur institute of Iran, Tehran, Iran. Microbiology Research Center (MRC), Pasteur institute of Iran, Tehran, Iran

Background: Staphylococcus aureus is a gram-positive bacterium and has been considered as an important nosocomial pathogen worldwide owing to its increasing antibiotic resistance. Carbon Nanotubes (CNTs) through their unique properties hold great promise in the fight against multidrug-resistant bacterial infections.Aim: In this study, Antimicrobial activity investigation of Multi-Walled carbon nanotubes on Staphylococcus aureus was done. Methods: Multi-wall carbon nanotubes were provided from US Research and were added to the 7H9 bacterial culture medium in the concentration range of %0.1 to %1. After a period of exposure, Anti-proliferation effect of CNTs was investigated by the Microplate Alamarblue Assay (MABA) method. Results:Antimicrobial potential of multi-wall carbon nanotubes on Staphylococcus aureus was found based on the color change associated with the specified concentration range on the bacterial growth rate. Conclusion: This study showed that multi-wall carbon nanotubes can have antimicrobial effects on Staphylococcus aureus although to get more accurate results, we are doing more specialized cellular and molecular investigation.

Antimicrobial activity, Staphylococcus aureus, Multi-walled carbon nano tubes (MWCNTs)