Marzieh Zamaniyan - M.D, Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran- Infertility Center, Department of Obstetrics and Gynecology, Mazandaran University of Medical Sciences, Sari, Iran
Samira Asgarirad - M.D, Medical Student, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran
Sepideh Peyvandi - M.D, Infertility Center, Department of Obstetrics and Gynecology, Mazandaran University of Medical Sciences, Sari, Iran

Introduction: In traditional IVF, several embryos are placed in the uterus to increase pregnancy rates.Transferring only one blastocyst is recommended to avoid this problem, but in low to middle incomecountries, facilities for blastocyst culture do not exist due to poorer quality control in IVF laboratories.Hence, the research question of the study is there any relationship between number of embryostransferred with pregnancy outcome Material and Methods: It was a retrospective cross-sectional study was carried out on infertile womenundergoing 591 IVF cycles that resulted in 212 pregnancies and 120 multiple pregnancies during 2011-2016.Results: Multiple pregnancy included 52 twin (43.3%) and 15 triplet pregnancies (12.5%), which finallyled to only 18 (15%) twin and 2 (1.7%) triple births. Moreover, 63 participants (52.5%) lost theiradditional embryos in utero throughout the pregnancy. No significant difference was observed betweennumber of oocytes and number of transferred embryos with type of delivery and pregnancy outcome,but, Significant differences were found between number of oocytes recovery and twin pregnancy rates(P=0.01)Conclusion: IVF had led to multiple pregnancies, but it did not always result in multiple births, becausemultiple factors such as abortion during pregnancy and probably poor laboratory conditions in lowresources countries result in loss of one or all of the embryos. Transfer of one to three macroscopicallygood quality embryos in utero is a reasonable option and does not increase considerably multiple birthsand preterm babies in such settings as compared to developed countries with advanced laboratoryconditions.

Multiple Birth Offspring; Fertilization in Vitro; Infertility; Embryo Transfer; Sperm Injections, Intracytoplasmic