Mohammad Dorchin - Dezful University of Medical Sciences.Dezful.Iran
Abdolkarim Sheikhi - Dezful University of Medical Sciences.Dezful.Iran
Mehrdad Akbari - Dezful University of Medical Sciences.Dezful.Iran

Background and Aim : Cancer causes many physical, psychological and social problems, including paintolerance and quality of life. The aim of this study was to determine the effectiveness of teaching stresscoping skills on the pain, quality of life of patients with breast cancer in Dezful.Methods : This is a semi-experimental study with a pretest-posttest design with a follow-up control group.For this purpose, 34 patients with study conditions were enrolled in the informal invitations. The patientswere randomly divided into two groups of 17 controls and controls. The experimental group was trained ina 8-week, 1.5-hour stress-coping skills (Lazarus and Folkman, 1984), and the control group received anormal program until the end of their normal program. Both groups completed the pain intensityquestionnaire before and after the program, and were evaluated in two stages in terms of the activity ofnatural lethal cells.Results : Descriptive results indicated a better status of the experimental group at the level of natural killercells and reduced the pain and its dimensions compared to the control group. The results of multivariatecovariance analysis with the control of the effect of pre-test showed that teaching stress coping skillsimproves the function of natural lethal cells in patients with breast cancer.Conclusion : The program also reduces the severity of pain and reduces pain interference in the dailyfunctioning of these patients.

coping with stress, immune system, Natural Killer Cells, pain, breast cancer