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Effects of low-dose contraceptive pills on the risk factors of cardiovascular diseases among 15-35-year-old women: A retrospective cohort

عنوان مقاله: Effects of low-dose contraceptive pills on the risk factors of cardiovascular diseases among 15-35-year-old women: A retrospective cohort
شناسه ملی مقاله: JR_IJRM-17-11_007
منتشر شده در شماره 11 دوره 17 فصل November در سال 1398
مشخصات نویسندگان مقاله:

zhran momeni - Deputy of Health, Bushehr University of Medical Sciences, Bushehr, Iran.Department of Biostatistics and Epidemiology, Faculty of Health, Shahid Sadoughi University ofMedical Sciences and Health Services, Yazd, Iran.
ali dehghani - Department of Biostatistics and Epidemiology, Faculty of Health, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
hossein Fallahzadeh - Department of Biostatistics and Epidemiology, Faculty of Health, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Moslem Koohgardi - Department of Health Education and Health Promotion, Faculty of Health, Rafsanjan University of Medical Sciences and Health Services, Kerman, Iran.
Maryam Dafei - Department of Midwifery, School of Nursing and Midwifery, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
Masoud Mohammadi - Department of Nursing, Faculty of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.

خلاصه مقاله:
Background: Cardiovascular diseases could be preventable; as a result, understanding the risk factors was regarded as the major priority for healthcare providers. Objective: The main objective of this research was to achieve a deeper insight into the effect of long-term use of low-dose oral contraceptive pills (OCP) on the risk factors of cardiovascular diseases. Materials and Methods: This research was a retrospective cohort conducted (historical and prospectively) conducted on 100 women with normal menstrual cycles aged 15 to 35 yr, who were referred to the healthcare centers in Yazd, Iran. The participants were categorized into two groups: The OCP group was consuming the pills for 0-3, 4-23, and 24-36 months, and the non-OCP group. Participants were followed up for a minimum of 3 months and a maximum of six months.Results: The highest level of low-density lipoprotein (LDL), homocysteine, cholesterol, triglyceride levels, and systolic blood pressure was observed in the OCP group in the duration of 24 to 36 months. The Tukey’s test demonstrated that there were comprehensible differences in the LDL (p = 0.01), cholesterol (p = 0.01), triglyceride (p < 0.001), and homocysteine levels (p < 0.001), also systolic blood pressure (p = 0.04). Conclusion: It was realized that the long-term consumption of low-dose OCP can augment the incidence of some risk factors (systolic blood pressure, homocysteine levels, cholesterol, LDL-c, and triglyceride) and lead to developing cardiovascular diseases amongst the healthy women.

کلمات کلیدی:
Birth control pills, Homocysteine, Nitric oxide, Dyslipidemias, Coronary artery diseases.

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/992488/