Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها

Systems Biology Analysis of the Key Genes of Surfactin Production in Bacillus subtilis MJ01 (Isolated from Soil Contaminated Oil in South of Iran), Spizizenii, and 168 Isolates

Year: 1396
COI: JR_JCMR-9-2_006
Language: EnglishView: 235
This Paper With 14 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 14 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:


Tahereh Deihimi - Institute of Biotechnology, Shiraz University, Shiraz, Iran
Esmaeil Ebrahimie - Institute of Biotechnology, Shiraz University, Shiraz, Iran- Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia
Ali Niazi - Institute of Biotechnology, Shiraz University, Shiraz, Iran
Mansour Ebrahimie - Department of Biology, University of Qom, Qom, Iran
Shahab Ayatollahi - School of Chemical & Petroleum Engineering, Sharif University of Technology, Tehran, Iran
Ahmad Tahmasebi - Department of Crop Production & Plant Breeding, College of Agriculture, Shiraz University, Shiraz, Iran


Applying microorganism in oil recovery has attracted attentions recently. Surfactin produced by Bacillus subtilis is widely used industrially in a range of industrial applications in pharmecutical and environmental sectors. Little information about molecular mechanism of suffactin compound is available. In this study, we performed promoter and network analysis of surfactin production genes in Bacillus subtilis subsp. MJ01 (isolated from oil contaminated soil in South of Iran), spizizenii and 168. Our analysis revealed that comQ and comX are the genes with sequencealterations among these three strains of Bacillus subtilis and are involved in surfactin production. Promoter analysis indicated that lrp, argR, rpoD, purr and ihf are overrepresented and have the highest number of transcription factor binding sites (TFBs) on the key surfactin production genes in all 3 strains. Also the pattern of TFBs among these three strains was completely different. Interestingly, there is distinct difference between 168, spizizenii and MJ01 in their frequency of TFs that activate genes involve in surfactin production. Attribute weighting algorithms and decision tree analysis revealed ihf, rpoD and flHCD as the most important TF among surfactin production. Network analysis identified two significant network modules. The first one consists of key genes involved in surfactin production and the second module includes key TFs, involved in regulation of surfactin production. Our findings enhance understanding the molecular mechanism of surfactin production through systems biology analysis.


Paper COI Code

This Paper COI Code is JR_JCMR-9-2_006. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Deihimi, Tahereh and Ebrahimie, Esmaeil and Niazi, Ali and Ebrahimie, Mansour and Ayatollahi, Shahab and Tahmasebi, Ahmad,1396,Systems Biology Analysis of the Key Genes of Surfactin Production in Bacillus subtilis MJ01 (Isolated from Soil Contaminated Oil in South of Iran), Spizizenii, and 168 Isolates,

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.


The specifications of the publisher center of this Paper are as follows:
Type of center: دانشگاه دولتی
Paper count: 21,774
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

New Papers

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.