Pyrrole Derivatives: Biological Activities and Synthesis Methods

Pyrroles and their derivatives are an important group of five-member heterocyclic compounds containing nitrogen atom that are the main component in many natural compounds have biological and medicinal properties. Compounds that contain the pyrrole ring have diverse biological activities. The classical methods for the synthesis of pyrrole derivatives include the Hantzsch, Knorr, and Paal-Knorr reactions. Due to the importance of pyrroles and their derivatives, synthesis of these compounds can be very important and a specific challenge for the chemists.

Keywords:

Pyrrole derivatives , Hantzsch , Knorr , Paal-Knorr , Synthesis