SM Javad Mortazavi - Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
Nima Bagheri - Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
Amirreza Farhoud - Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
Saeid Hadi Kalantar - Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran

Total knee arthroplasty is considered as the treatment of choice for those with end stage hemophilic arthropathy.Compared to other patients undergoing TKA, these patients have specific features such as bleeding tendency, youngerage, pre-operative restricted range of motion (ROM), altered anatomy, and increased complications. This narrativereview of literature is going to investigate several issues regarding the TKA in hemophilic patients including indications,perioperative factor replacement, surgical challenges, postoperative rehabilitation, outcomes, and complications.Level of evidence: I

Hemophilia, hemophilic arthropathy, TKA, Total knee arthroplasty