ناشر تخصصی کنفرانس های ایران

لطفا کمی صبر نمایید

Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها
Paper
Title

The Protective Effects of genistein on Nicotine-induced Changes in Rats Ovarian Follicles

Year: 1399
COI: ICMWMI01_003
Language: EnglishView: 257
This Paper With 7 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 7 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:

Authors

Azita alijamaat - Faculty of veterinary medicine University of Tabriz Tabriz, Iran
Sina moshtagh - Faculty of veterinary medicine Islamic azad university of Tabriz Tabriz, Iran

Abstract:

Background: Nicotine exposure causes impaired fertility and ovarian dysfunction. The aim of this study was to investigate the possible protective role of genistein, which is known as an antioxidant agent on altered ovarian functions upon nicotine exposure.Methods: A total of 40 female adult vistar rats were divided randomly into four groups (n=10). The control group received vehicle, while group 2 received nicotine (40 μg/kg) for 15 days and group 3 genistein (5 mg/kg) for 5 days. Group 4 received both nicotine (40 μg/kg) and genistein (5 mg/kg) for the same periods. All animals were treated intraperitoneal. After autopsy on the 16th day, histopathological and morphometrically examinations were performed and serum estradiol concentrations were measured. The data were analyzed using ANOVA and Tukey post hoc test. A value of p<0.05 was considered significant.Results: Nicotine significantly reduced the number of pre-antral and antral follicles, as well as estradiol concentration compared to the control group (p<0.05). However, the decrease in the number of primordial follicles was not significant in the nicotine treated group. A significant increase in the follicles atresia were observed in group 2 compared to the control group (p<0.05). Moreover, genistein caused a marked normalization in the number of ovarian follicles and estradiol levels in group 4 compared to group 2.Conclusion: The results from this study suggest that genistein may have a protective effect against nicotine-induced ovarian changes on the number of different stages of follicle growth.

Keywords:

Paper COI Code

This Paper COI Code is ICMWMI01_003. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1030836/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
alijamaat, Azita and moshtagh, Sina,1399,The Protective Effects of genistein on Nicotine-induced Changes in Rats Ovarian Follicles,International Conference on New Findings in Midwifery, Women, Childbirth and Infertility,https://civilica.com/doc/1030836

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.

Scientometrics

The specifications of the publisher center of this Paper are as follows:
Type of center: دانشگاه دولتی
Paper count: 20,946
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

New Papers

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.

Support