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Title

The Effect of Short-Range Radiation of Type C and B Ultraviolet on the Mechanical Properties of Skin Fibroblasts

Year: 1398
COI: JR_JCAM-50-2_018
Language: EnglishView: 569
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Authors

Amirhossein Azami - Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
Ashkan Heydarian - Science and Research Branch, Daneshgah Blvd, Simon Bulivar Blvd, Tehran
armin Jarrahi Khameneh - Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
Siamak Khorramymehr - Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran

Abstract:

The effect of UV beam, which has been emitted from a natural or a manmade source on cells has been studied in previous studies for several times. Radiation of this beam can have different effects on DNA of the cell, cytotoxicity, the structure of cellular proteins and their mechanical properties based on radiation period or frequency. The effect of radiation of two types of beams, namely UVB and UVC on stiffness and deformation of the cell are studied in such studies based on different durations of radiation. Viscoelastic properties of skin fibroblast cells were measured using the magnetic tweezer method for a number of groups under UVC radiation with radiation durations of 38, 60 and 120 seconds and for a group under UVB radiation with radiation duration of 38 seconds, also for a control group. In addition, three and four-element discrete differential models were used for creep analysis. Cells deformation had a considerable change after radiation, while such deformation decreased as the frequency increased, however, no comment can be stated regarding radiation duration. Furthermore, cell stiffness reduced after radiation. Such decrease in cell stiffness after radiation could be due to the destruction of the biological macromolecules bonds. Furthermore, the extent of cell deformation was much lower in the radiation groups in comparison to the control group.

Keywords:

Paper COI Code

This Paper COI Code is JR_JCAM-50-2_018. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1031978/

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Azami, Amirhossein and Heydarian, Ashkan and Jarrahi Khameneh, armin and Khorramymehr, Siamak,1398,The Effect of Short-Range Radiation of Type C and B Ultraviolet on the Mechanical Properties of Skin Fibroblasts,https://civilica.com/doc/1031978

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