N,N,N ,N -Tetramethyl-N,N -bis(sulfo)ethane-1,2- Diaminium Mesylate ‎as a Highly Effective and Dual-functional Catalyst for the Synthesis of 1-Thioamidoalkyl-2-naphthols

N,N,N ,N -tetramethyl-N,N -bis(sulfo)ethane-1,2-diaminium mesylate ‎‎([TMBSED][Oms]2) is ‎used as a highly efficient and dual-functional catalyst for the one-pot multi-component ‎condensation of 2-naphthol with arylaldehydes and thioacetamide under green, mild (70 °C), ‎and solvent-free conditions. In this reaction, 1-thioamidoalkyl-2-naphthols are produced in ‎high to excellent yields and in relatively short reaction times. In this reaction, products ‎are identified by analysis of its 1H NMR, 13C NMR, and FT-IR data.‎ Moreover, a plausible mechanism based on dual-functionality of the catalyst was proposed.

Keywords:

N , N , N , N -tetramethyl-N , N -bis(sulfo)ethane-1 , 2-diaminium mesylate ‎‎([TMBSED][Oms]2)‎ , ‎Thioacetamide , 1-Thioamidoalkyl-2-naphthol , Multi-component ‎reaction , Dicationic ionic liquid , Dual-functional ‎catalyst.‎