The Effect of Aquous Extract of Cariandrum Sativum on Fetal Weight and Height in Pregnant Mice
Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJNS-4-3_006
تاریخ نمایه سازی: 11 مرداد 1399
Abstract:
Background: Herbal medicine may have irreparable effects on fetal development. This study investigated the effect of Cariandrumsativum (coriander) aquous extract on mice fetal height and weight. Methods:In an experimental study, 120 pregnant mice were divided into four equal groups. The control group was without any intervention. The experimental group received 3500, 5000 and 6500 mg/kg of aquous extract of coriander. The height and weight of the embryos were recorded in first, second and third week of pregnancy. Results: The height and weight of embryos in experimental groups in first, second and third week was significantly lower than the control group. Conclusion: Coriander (C. Sativum) aquous extract was shown to reduce the fetal height and weight in a dose-dependent manner. These findings can be added to the literature when coriander is going to be used during pregnancy.
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Authors
Davood Mehrabani
Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran|Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran|Comparative and Experimental Medicine Center, Shiraz University
Mahnaz Mehrmand
Science and Research Branch, Islamic Azad University, Fars, Iran
Akbar Vahdati
Science and Research Branch, Islamic Azad University, Fars, Iran
Mehdi Pasalar
Traditional Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran