Mahnaz Hashemipour - Shahrood University of Technology, Shahrood, Iran
Ali Keivanloo - Shahrood University of Technology, Shahrood, Iran

An efficient approach described for the synthesis of highly substituted imidazoles in the presence of ZnCl2/urea as an efficient catalyst through multi-component reaction under solvent-free conditions. The advantages of this one-pot procedure are experimental simplicity, easy work-up, and affords desired products with high to excellent yields. Furthermore, this procedure is highly sustainable because of the employment of readily available and biodegradable deep eutectic solvent.

Deep eutectic solvent, Multi-component synthesis, imidazole, Solvent-free