Mohammad Fazilati۱ - Payam noor university of Isfahan,Isfahan,Iran
Hamidreza Dastjed۱ - Payam noor university of Isfahan,Isfahan,Iran

Nanotechnologyoffered a new toolset for the discovery, engineering and manufacturing of nanopatterned surfaces, and nanostructured scaffolds for implantable devices. Moreover, nanotechnology offers novel and improved solutions for the localized release of the biomolecules and growth factors that are needed in any tissue engineering approach. Nanotechnology in tissue engineering overcomes many downfalls that micron structured implants face, such as infection, chronic inflammation, and poor binding with the surrounding tissue. To improve these issues, nano-scale features have been implemented, providing enhanced biointegration. Natural tissues contain various nanometer features because of the presence of collagen fibrils and other proteins that are less than 100 nm in one dimension. The nanometer-scaled surface structures enhance cellular response through mimicking natural tissue. Due to the tunability and adaptability of the manufacturing processes, several different scaffold types can be obtained and ideally optimized for the particular needs and requirements of the individual patient or application

Nanostructure, biomolecules biointegration, mimicking, tissue engineering