Industrially manufacturing process for the synthesis of Azithromycin dihydrate, as an effective macrolide antibiotic

Publish Year: 1399
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:

CBGCONF07_116

تاریخ نمایه سازی: 22 آذر 1399

Abstract:

The present study describes a high yield procedure for the industrially production of the Azithromycin in itscrystalline dihydrate form. The physicochemical properties of synthesized sample were investigated using variousanalyses methods, including XRD, KFT, UV–vis, FTIR, 1H and 13C NMR and HPLC. This procedure represented anacceptable yield about 1.00 (based on Aza-Erythromycin weight) with 98.7% purity of Azithromycin dihydrate.

Authors

Mohammad Darzinezhad

Antibiotic Sazi Iran Company

Yadollah Nasiri

Antibiotic Sazi Iran Company

Marzieh Sadatshahabi

Antibiotic Sazi Iran Company

Maryam Molkara

Antibiotic Sazi Iran Company