Alireza Heidari Bakavoli - Cardiologist, Cardiovascular Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Alireza Ghodsi - Medical student, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Alireza Omranzadeh - Medical student, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Moniba Bijari - Medical student, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Sara Hosseini - Cardiologist, Cardiovascular Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Sofosbuvir is an antiviral drug that entirely revolutionized the treatment of hepatitis C. This drug has an Iranian commercial brand, which is known as Ledibiox. Several adverse events have been reported with this drug, including syncope, pancolitis, and exacerbated pulmonary arterial hypertension; however, arrhythmia rarely has been described through the literature. Here, we report a 40-year-old Caucasian man who presented with chest pain, tachycardia, blurred vision, and severe headache; whose electrocardiography showed an atrial tachycardia along with a block. It seems that Sofosbuvir toxicity can cause arrhythmia, and the drug prescription should be halted in this situation.

Arrhythmia, Cardiac, ledipasvir/sofosbuvir, Ledibiox