Maryam Deldar Pasikhani - Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
Fahimeh Ghotbizadeh - Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
Razieh Akbari - Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
Mahshid Shooshtari - Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
Atieh Pajouhi - Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

Background & Objective: Anticoagulant therapy has been used for the prevention and treatment of deep vein thrombosis and pulmonary embolism. Heparin-induced necrotizing skin lesion is a serious complication that can be potentially life-threatening. Case Report: We report a 55-year-old female presenting with skin necrosis without thrombocytopenia after prescribing heparin prophylaxis. She had died as it was not possible to discontinue her heparin therapy. Conclusion: Heparin-induced skin necrosis should be suspected in all patients who undergo UFH or LMWH. Observation of platelet count is recommended at the onset of skin lesions. Early diagnosis of this condition can be helpful for the management of this potentially mortal disease.

Anticoagulants, Heparin, Necrotic Skin lesions