Survival and Factors Affecting it in Lung Cancer Patients Referred to Imam Khomeini Clinic in Hamadan Province

Background: Lung cancer is one of the most common cancers and the leading cause of death due to cancer in the world. It has the highest mortality rate compared to breast, prostate, and other cancers. Different factors can be effective in the survival of lung cancer patients. The present study has evaluated survival and its related factors. Materials and Methods: The present study was performed on ۱۵۷ lung cancer patients referred to Imam Khomeini Specialized Clinic in Hamadan during ۲۰۰۳-۲۰۱۷. Patient follow-up was performed through periodic referrals and telephone calls with patients’ relatives. The survival rate was evaluated using Kaplan-Meier method and the log-rank test was used to compare the survival of different levels of variables. Data analysis was then carried out using SPSS version ۲۳.۰ and STATA version۱۴.۰. P value < ۰.۰۵ was considered statistically significant in all tests. Results: Of ۱۵۷ patients with lung cancer, ۸۶% were male. The mean and median survival times of patients were ۱۵ and ۱۱ months, respectively. The results of log-rank test indicated that metastasis and site of metastasis were effective in patient survival (P < ۰.۰۵). Conclusion: The results of the present study showed that the presence of metastasis is a strong factor for the survival of patients; therefore, it seems necessary to diagnose the disease as early as possible using a screening program.

Keywords:

Lung Cancer , Survival analysis , Kaplan-Meier , Hamedan