Effect of High Intensity Interval Training and Honey Consumption on Some Inflammatory Indices in Sedentary Subjects

Background: The sedentary lifestyle has been introduced as one of the main causes of disease and a predictor of morbidity and mortality. Inflammation is an essential contributor to the pathogenesis of diseases. The aim of the present study was to investigate the effect of high-intensity interval training and honey consumption on IL-۶, IL-۱۲ and TNF-a levels in sedentary individuals. Methods: Thirty-eight young, healthy and inactive men were assigned to one of the following interventions: Exercise+placebo (EP), Exercise+Supplement (ES), Supplement (S) and Placebo (P). Subjects in the exercise groups underwent a supervised HIIT program over ۸ weeks. Exercise at each session comprised ۲ min high intensity training with the intensity of ۸۰-۹۰% of heart rate max interspersed by lowintensity intervals of walking for ۱ minute. Throughout the study, the subjects in supplement groups received ۵ cc/kg body mass of ۱۳% honey dissolved in plain water within ۳۰-۶۰ min before each exercise session. The subjects in placebo groups were administered with an equal volume of water solution with ۵ gr sucrose. Before and ۷۲h after the experimental period blood samples were collected to assess plasma levels of IL-۶, IL-۱۲, and TNF-a. Results: We observed that IL-۶ levels significantly decreased in ES and E groups from pretest to posttest and there was a significant difference between the ES and control groups (Pvalue=۰.۰۲۳). However, no significant changes were observed for IL-۱۲ and TNF-a (Pvalue>۰.۰۵). Conclusions: HIIT program along with honey consumption over ۸ weeks could have favorable effects on inflammatory indices such as IL- ۶ in subjects with sedentary life-style.

Keywords:

HIIT , Honey , Inflammation , IL-۶ , TNF-α , IL-۱۲