Vaginal Adenosis in Two Patients with No History of Diethylstilbestrol: A Case Report

Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JOGCR-5-4_007

تاریخ نمایه سازی: 27 دی 1399

Abstract:

Introduction: Vaginal adenosis is one of the precursor lesions of the vaginal clear cell adenocarcinoma (CCA). The most common symptom of vaginal adenosis is abnormal vaginal pain and bleeding. About 90% of women exposed to diethylstilbestrol (DES) during pregnancy have vaginal and cervical adenosis in female fetus. DES has been reported rarely with no history of fetal use. Case Presentation: In this article, we report two vaginal adenosis patients with no history of DES during pregnancy. There was no vaginal cancer in the follow-up of the patients. Conclusion: Vaginal adenosis is considered as a non-common differential diagnosis of vaginal bleeding that can be diagnosed by physical examination, colposcopy, and biopsy.

Authors

Maliheh Hasanzadeh

Department of Obstetrics and Gynecology, Fellow of Gynecology Oncology, Women’s Health Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Seyedeh Sara Nourbakhsh

Medical Student, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Amir Hosein Jafarian

Associate Professor, Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Parnian Malakuti

Medical Student, Faculty of Medicine, Szeged University of Medical Sciences, Szeged, Hungary