Marie Saghaeian Jazi - Stem Cell Research Center, Golestan University of Medical Sciences, Gorgan, Iran

Summary: SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA associated with cancer pathogenesis. It contributes to a variety of cellular functions and recent evidence propounds its association with autophagy process. It has been showed that SOX2OT can regulate the expression of different autophagy associated factors in human cells with different mechanisms, however more remains to be investigated.

SOX2OT, lncRNA, Autophagy