Anti-tumor Effects of Essential Oils of Red Clover and Ragweed on MCF-7 Breast Cancer Cell Line

Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
View: 239

This Paper With 7 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

این Paper در بخشهای موضوعی زیر دسته بندی شده است:

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_MCIJO-1-4_004

تاریخ نمایه سازی: 28 بهمن 1399

Abstract:

Introduction: Breast cancer is one of the most common malignancies among Iranian women. Nowadays, the use of traditional medicinal plants has emerged as a tempting complementary to the treatment of breast cancer due to minimal side effects and less documented drug resistance. The aim of this study was to examine the anticancer effects of the essential oils of red clover and mature fruit of Bassia scoparia on MCF-7 cells. Methods: Essential oils were extracted from Bassia scoparia and red clover plants, by a Clevenger condenser and mass spectrometry was performed for qualitative analysis, then MCF-7 and HU02 cells were treated with different concentrations of these essential oils at different time intervals. The viability of cells was measured by the MTT assay. The results were analyzed using the one-way ANOVA and Tukey′s test. Results: Essential oils of Kochia scoparia and red clover have cytotoxic effects on MCF7 cells. The MTT analysis showed decreased cell viability percentage in treated cells (P <0.05). In addition, the microscopic examination of cells treated with essential oils revealed morphological changes of apoptotic cells in MCF-7 cells. Conclusions: The findings of this study show that essential oils of Bassia scoparia and red clover have toxic and anticancer effects on MCF-7 cells.

Authors

Fatemeh Kianinodeh

High Institution for Research and Education in Transfusion Medicine, Tehran, Iran

Mahdi Tabatabaei

Department of Laboratory Sciences, College of Science of Borujerd, Islamic Azad University, Iran and Young Researchers and Elite Club, Borujerd Branch, Islamic Azad University, Borujerd, Iran

Atena Alibakhshi

Department of Laboratory Sciences, College of Science of Borujerd, Islamic Azad University, Iran

Mahshid Gohari

Department of Laboratory Sciences, College of Science of Borujerd, Islamic Azad University, Iran

Kaveh Tari

Cancer and Immunology Center, Kurdistan University of Medical Sciences Sanandaj, Iran

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • 1. Vo AT, Millis RM. Epigenetics and breast cancers. Obstet ...
  • 2. Pathy NB, Yip CH, Taib NA, Hartman M, Saxena ...
  • 3. Tucak M, Popović S, Čupić T, Krizmanić G, Španić ...
  • 4. Du WH, Tian XH, Yue Y, Lu J. Isoflavone ...
  • 5. Kafi M, Salehi M. Kochia Scoparia as a Model ...
  • 6. Han HY, Kim H, Son YH, Lee G, Jeong ...
  • 7. Han HY, Lee HE, Kim HJ, Jeong SH, Kim ...
  • 8. Khandelwal KR. Practical pharmacognosy: Pragati Books Pvt. Ltd.; 2008. ...
  • 9. Omidbeygi M, Barzegar M, Hamidi Z, Naghdibadi H. Antifungal ...
  • 10. Lambert RJ, Skandamis PN, Coote PJ, Nychas GJ. A ...
  • 11. Vlaisavljevic S, Kaurinovic B, Popovic M, Djurendic-Brenesel M, Vasiljevic ...
  • 12. Mazzio EA, Soliman KF. In vitro screening for the ...
  • 13. Wang J, Yuan L, Xiao H, Xiao C, Wang ...
  • 14. Matsuda H, Li Y, Yamahara J, Yoshikawa M. Inhibition ...
  • 15. Chen YN, Chen JC, Yin SC, Wang GS, Tsauer ...
  • نمایش کامل مراجع