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Title

Biological Aspects and Clinical Applications of Nanoparticles on Treatment and Prophylaxis of HIV

Year: 1399
COI: JR_IJMM-14-6_001
Language: EnglishView: 122
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Authors

Mohammad Saeedi - Department of Laboratory Science, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran
Fatemeh Mehranfar - Department of Laboratory Science, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran
Shaghayegh Omidi Omidi - Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran
Fatemeh Zahra Ehsani - Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran
Omid Pajand Pajand - Department of Microbiology, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran

Abstract:

Acquired Immune Deficiency Syndrome (AIDS) is a descriptive type of immune system dysfunction disorder which is caused by HIV infection. Since its discovery, HIV has been responsible for the death of more than 25 million people worldwide, and many people are infected with HIV each year. Because of the structural complexity of the virus and the lack of a promising vaccine, several antiviral drugs, and nucleic acid therapies such as siRNA have been studied and evaluated for the HIV prevention. The antiviral treatments have considerably improved the quality and hope of life for the infected people, but along with the capacity to adapt to the virus, it has prevented further success. Nanotechnology approaches have had a positive impact on the prevention and treatment of different diseases. Various nanoparticles and substances have been evaluated for the antiviral drugs improvement for the prophylaxis and treatment of AIDS. Some nanoparticles which have been discussed in this article include liposomes, dendrimers, gold nanoparticles, polymeric nanoparticles, nanofibers, silver nanoparticles, and drug nanocrystals. In this review study, the nanotechnology approaches, the structure and properties of nanoparticles and their function in the prophylaxis and treatment of HIV were discussed.

Keywords:

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This Paper COI Code is JR_IJMM-14-6_001. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

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Saeedi, Mohammad and Mehranfar, Fatemeh and Omidi, Shaghayegh Omidi and Ehsani, Fatemeh Zahra and Pajand, Omid Pajand,1399,Biological Aspects and Clinical Applications of Nanoparticles on Treatment and Prophylaxis of HIV,https://civilica.com/doc/1159269

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