Synthesis, characterization and crystal structure of pyridine carbaldehyde thiosemicarbazone Schiff base ligand

For decades, Schiff bases have been played an important role as chelating ligands in main group and transition metal coordination chemistry, due to their easy synthesis, wide availability and structural versatility associated with their potential applications in catalysis, electronics, and magnetism1. The semicarbazones and thiosemicarbazones usually behave as chelating ligands, which are versatile in both neutral and anionic forms2. Furthermore, the metal complexes of semicarbazones have demonstrated antimicrobial, anticancer, and antiviral activities3. Herein we synthesized and characterized a new thiosemicarbazone ligand from the reaction of thiosemicarbazide and pyridine carbaldehyde under reflux conditions. The HL is characterized fully. Furthermore, the structure of new ligand characterized by X-ray crystallography. The compound crystallizes in a Monoclinic system, with space group P21/n. Single X-ray crystal analysis reveals that new ligand consists of a Schiff base molecule and one methanol molecule. The self-assembly observed in the extended structure through several labile interactions

Keywords:

Schiff bases thiosemicarbazone , Crystal Structure.