New, stable and reusable magnetic Fe3O4/PEG@CPTMS-thioaminophenol@Ni nano catalyst for the synthesis of dispiro-cyclopropanes’s Meldrum’s acid

Fe3O4/polyethylene glycol (PEG-400), which is supply as a core-shell magnetic particles reason to their superficial space and immediate reclamation contain newly arisen as catalyst backings 1 Hybrid inorganic – organic magnetized nanoparticles had constantly reading case reason to their biomedical utilization, to protein separation 2 therapeutic transfer of DNA and drugs 3 inhibition their aggregation by build a clog barrier among they prepared biocompatibility, renderer probable for link aim region and avoid the reconnoiter 4 PEG is a biotic biocompatible polymer and is utilization as cover for nanoparticles which is an egregious between the more proper polymers because of its remarkable attribute for instance, greatly hydrophilic nature (hydrophilicity), flexibility and adaptability, dangerless and nonimmunogenicity 5.

Keywords:

Fe3O4 , Dispiro-cyclopropane , Meldrum’s acid , 2-Amino thiophenol