Synthesis of benzo[g]chromene derivatives in the presence of nano Cu-MOF

The discovery of Metal Organic Framework (MOF), a new family of porous crystalline compounds, has attracted a lot of attention in the last two decades, as these compounds are capable of commercial application.1 Recently, the use of MOFs as heterogeneous catalysts in organic reactions has been considered more than before because these compounds are unique in their structure due to the presence of metal and an organic ligand in their structures.2 In order to the easy separation and recycling of heterogeneous catalysts, its use in multicomponent reactions (MCRs) is of particular importance3. Herein, we report the synthesis of benzo[g]chromene derivatives 4 from the reaction between lawsone 1, aldehydes 2 and Malononitrile 3 in the presence of nano Cu-MOF as catalyst in EtOH under reflux. The synthesized catalyst was characterized by SEM, PXRD, TGA and N2 adsorption/desorption isotherms techniques.

Keywords:

Multicomponent reactions , Benzo[g]chromene , Metal organic framework , Nanocatalyst.