Seyedeh Fatemeh Hojati - Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran
Amirhassan Amiri, - Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran
Sara Ghavidel - Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran

The pyridine rings have been found in the structure of many natural products such as nicotinic acid, vitamin B6, and NAD nucleotides.1 In recent years, various methods have been used for the synthesis of pyridine derivatives. But one of the best methods for the preparation of pyridine derivatives is the use of multicomponent reactions. In recent years, the synthesis of pyridine compounds has been carried out using various catalysts such as H14[NaP5W30O110],2 Bi(OTf)3,3 MgAl2O4,4 ZrOCl2,5 CoCl2 6H2O.6Although some of these methods are valuable, most of them have several disadvantages such as long reaction times, requiring large amounts of catalyst and the use of toxic or non-reusable reagent. Therefore, development of a facile and economical synthetic route to 2,4,6-triarylpyridines is still in demand. Herein, we apply a copolymer coated magnetic graphene oxide for the first time as a green and reusable nanocatalyst in the synthesis of these biologically active heterocycles from benzaldehydes, acetophenones and ammonium acetate in solvent-free conditions

2,4,6–Triaryl pyridine, Multicomponent reactions, Solvent-free conditions.