Joulia Alizadeh-Rahrovi - Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
Azadeh Ebrahim-Habibi - Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences,Tehran, Iran

Investigating the proteins at the atomic level enables the protein dynamics to be described at the microscopic level. This can lead to obtain the macroscopic parameters of a protein studying in the desired conditions. Here molecular dynamics (MD) simulation has been used as a practical tool to study the characterization and the conformational changes of a protein, especially in the studies of protein unfolding process[1,2].