Effects of Mallow, (Malva Sylvestris) Extract on Reducing Anxiety in Animal Model

Background: Anxiety is an unpleasant and obscure sense of fear with unknown origin. It is characterized by distrust, prostration, and physiological arousal which is associated with one or more signs or symptoms such as nausea, chest tightness, palpitation, sweating, and headache. The purpose of this study was to evaluate the effects of mallow’s extract on reducing dark anxiety in mice.  Materials and Methods: Forty laboratory mice were divided into 5 treatment groups: control, dark anxiety, and 50, 100, and 200 mg/kg doses of the mallow’s extract. Results: Based on the results, anxiety decreases significantly spending time in open arm while all doses of mallow extract increases it. Also, anxiety reduces mean open arm entrance and the extract increases it in all doses.  Conclusion: According to results, hydroalcoholic extract of mallow could reduce the anxiety in 100 and 200 mg/kg groups by effecting nervous system.

Keywords:

Mallow hydroalcoholic extract , Anxiety , Mice