The exact synchronization timing between the cleavage embryo stage and duration of progesterone therapy improved pregnancy rates in frozen embryo transfer cycles: a retrospective study

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نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_IJRM-19-3_002

تاریخ نمایه سازی: 17 فروردین 1400

Abstract:

Background: Synchronization between the embryonic stage and the uterine endometrial lining is important in the outcomes of the vitrified-warmed embryo transfer (ET) cycles. Objective: The aim was to investigate the effect of the exact synchronization between the cleavage stage of embryos and the duration of progesterone administration on the improvement of clinical outcomes in frozen embryo transfer (FET) cycles. Materials and Methods: 312 FET cycles were categorized into two groups: (A) day-3 ET after three days of progesterone administration (n = 177) and (B) day-2 or -4 ET after three days of progesterone administration (n = 135). Group B was further divided into two subgroups: B1: day-2 ET cycles, that the stage of embryos were less than the administrated progesterone and B2: day-4 ET cycles, that the stage of embryos were more than the administrated progesterone. The clinical outcome measures were compared between the groups. Results: The pregnancy outcomes between groups A and B showed a significant differences in the chemical (40.1% vs 27.4%; p = 0.010) and clinical pregnancies (32.8% vs 22.2%; p = 0.040), respectively. The rate of miscarriage tended to be higher and live birth rate tended to be lower in group B than in group A. Also, significantly higher rates were noted in chemical pregnancy, clinical pregnancy, and live birth in group A when compared with subgroup B2. Conclusion: Higher rates of pregnancy and live birth were achieved in day-3 ET after three days of progesterone administration in FET cycles.  

Authors

Marjan Omidi

Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Iman Halvaei

Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Fatemeh Akyash

Stem Cell Biology Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Science, Yazd, Iran.

Mohammad Ali Khalili

Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Azam Agha-Rahimi

Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Leila Heydari

Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

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  • Gomaa H, Casper RF, Esfandiari N, Bentov Y. Non-synchronized endometrium ...
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  • Balaban B, Urman B, Ata B, Isiklar A, Larman MG, ...
  • Debrock S, Peeraer K, Fernandez Gallardo E, De Neubourg D, ...
  • Paulson RJ. Hormonal induction of endometrial receptivity. Fertil Steril 2011; ...
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  • Groenewoud ER, Macklon NS, Cohlen BJ, ANTARCTICA trial study group. ...
  • Groenewoud ER, Cantineau AE, Kollen BJ, Macklon NS, Cohlen BJ. ...
  • Kim HH, Matevossian K. It's all about timing: Is the ...
  • Sahmay S, Oral E, Saridogan E, Senturk L, Atasu T. ...
  • Coutifaris C, Myers ER, Guzick DS, Diamond MP, Carson SA, ...
  • Eftekhar M, Bagheri Baradaran R, Neghab N, Hosseinisadat R. Evaluation ...
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  • Givens CR, Markun LC, Ryan IP, Chenette PE, Herbert CM, ...
  • Van De Vijver A, Polyzos NP, Van Landuyt L, Mackens ...
  • Sharma S, Majumdar A. Determining the optimal duration of progesterone ...
  • Ding J, Rana N, Dmowski WP. Length of progesterone treatment ...
  • Prapas Y, Prapas N, Jones EE, Duleba AJ, Olive DL, ...
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