Leydig Cell Tumor in Children: a Case Report and Literature Review

Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
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JR_TUMS-2-2_001

تاریخ نمایه سازی: 17 فروردین 1400

Abstract:

IntroductionLeydig cell tumors (LCTs) comprising of 1 to 3 percent of testicular cancers in children, one of the single most common symptom in prepubertal patients is painless testicular swelling with or without a sign of precocious puberty. Other symptoms depend on age and the type of tumor. The tumor is usually asymptomatic if secrets androgens can cause precocious puberty in young children. If the tumor secretes estrogens, it can cause rarely gynecomastia in young boys.Case presentationHere we are reporting pure LCTs in a ten-year-old boy presented with gynecomastia. His height and weight were in the normal range. Differential diagnosis of large cell calcifying Sertoli cell or Leydig cell tumor, teratomas and revealed the normal size and echogenicity of both epididymis confirmed the Leydig cell tumor.ConclusionsDue to the extremely variable clinical presentation tumor especially children and the importance of maintaining the fertility in this group and increased incidence of malignancy, especially in adolescence early detection and timely treatment are crucial.

Authors

Khashayar Atqiaee

Department of Pediatric Surgery, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran

Arash Mohammadi Tofigh

Department of General Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Shahab Salehpour

Clinical Research Development Unit (CRDU) of Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Alireza Mirshemirani

Pediatric Surgery Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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