Effect of alpha-lipoic acid supplementation on the lipid profile and lipid ratios in women with gestational diabetes mellitus: A clinical trial study

Publish Year: 1399
نوع سند: مقاله ژورنالی
زبان: English
View: 269

This Paper With 10 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

این Paper در بخشهای موضوعی زیر دسته بندی شده است:

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_IJRM-18-12_003

تاریخ نمایه سازی: 17 فروردین 1400

Abstract:

Background: Evidence suggests that Oxidative stress has been shown to plays an important role in gestational diabetes mellitus (GDM) etiology. On the other hand, women with GDM are at an increased risk for complications such as endothelial dysfunction and cardiovascular diseases. Objective: To investigate the effects of alpha-lipoic acid (ALA) on the maternal circulating values of lipid profile and lipid ratios in women with GDM. Materials and Methods: Sixty women with GDM were participated in the present study. The ALA group (n = 30) received ALA (100 mg/day) and the placebo group (n = 30) received cellulose acetate (100 mg/day) for eight wk. The maternal circulating values of hemoglobin A1C, triglyceride (TG), total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, triglyceride-glucose (TyG) index, atherogenic index of plasma (AIP), non-HDL-C, and lipid ratios were assessed before and after the intervention. P-value < 0.05 was considered as statistically significant. Results: The values of TyG index (p < 0.001), TG (p = 0.006), TG/HDL-C (p = 0.003), and AIP (p = 0.005) decreased significantly in the ALA group after the intervention. Conclusion: Maternal circulating values of TyG index, TG, TG/HDL, AIP decreased after eight wk of ALA supplementation in women with GDM.

Authors

Hadise Aslfalah

Students Research Committee, Arak University of Medical Sciences, Arak, Iran.

Mehri Jamilian

Department of Gynecology and Obstetrics, Endocrinology and Metabolism Research Center, School of Medicine, Arak University of Medical Sciences, Arak, Iran.

Hadi Ansarihadipour

Department of Biochemistry and Genetics, Endocrinology and Metabolism Research Center, School of Medicine, Arak University of Medical Sciences, Arak, Iran.

Mahdi Abdollahi

Decorative and Hygienic Products, Control Laboratory of Food, Beverage, Food and Drug Administration, Arak University of Medical Sciences, Arak, Iran.

Ali Khosrowbeygi

Department of Biochemistry and Genetics, Endocrinology and Metabolism Research Center, School of Medicine, Arak University of Medical Sciences, Arak, Iran. Traditional and Complementary Medicine Research Center (TCMRC), Arak University of Medical Sciences

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • Abbasi M, Mazloum Khorasani Z, Etminani K, Rahmanvand R. Determination ...
  • Lappas M, Hiden U, Desoye G, Froehlich J, Hauguel-de Mouzon ...
  • Ghate J, Choudhari AR, Ghugare B, Ramji S. Antioxidant role ...
  • Monastra G, De Grazia S, Cilaker Micili S, Goker A, ...
  • Derosa G, D'Angelo A, Romano D, Maffioli P. A clinical ...
  • Zhang Y, Han P, Wu N, He B, Lu Y, ...
  • Akbari M, Ostadmohammadi V, Lankarani KB, Tabrizi R, Kolahdooz F, ...
  • Di Tucci Ch, Di Feliciantonio M, Vena F, Capone C, ...
  • Di Fulvio P, Pandolfi A, Formoso G, Di Silvestre S, ...
  • Contreras-Duarte S, Carvajal L, Garchitorena MJ, Subiabre M, Fuenzalida B, ...
  • Jasper R, Skelding K. Cardiovascular disease risk unmasked by pregnancy ...
  • American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes ...
  • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration ...
  • Niroumand Sh, Khajedaluee M, Khadem-Rezaiyan M, Abrishami M, Juya M, ...
  • Pazhohan A, Rezaee Moradali M, Pazhohan N. Association of first-trimester ...
  • Gasevic D, Frohlich J, Mancini GJ, Lear SA. Clinical usefulness ...
  • Pfalzgraf A, Frigg M, Steinhart H. Alpha.-tocopherol contents and lipid ...
  • Siangproh W, Rattanarat P, Chailapakul O. Reverse-phase liquid chromatographic determination ...
  • De Cicco S, Immediata V, Romualdi D, Policola C, Tropea ...
  • Noori N, Tabibi H, Hosseinpanah F, Hedayati M, Nafar M. ...
  • Li Y, Ma QG, Zhao LH, Wei H, Duan GX, ...
  • Bao XH, Xu J, Chen Y, Yang CL, Ye ShD. ...
  • Chang JW, Lee EK, Kim TH, Min WK, Chun S, ...
  • Porasuphatana S, Suddee S, Nartnampong A, Konsil J, Harnwong B, ...
  • Di Tomo P, Di Silvestre S, Cordone VGP, Giardinelli A, ...
  • Jin JL, Sun D, Cao YX, Guo YL, Wu NQ, ...
  • Wu TT, Gao Y, Zheng YY, Ma YT, Xie X. ...
  • Gasevic D, Frohlich J, Mancini GBJ, Lear SA. The association ...
  • dos Santos-Weiss ICR, Réa RR, Fadel-Picheth CMT, Rego FGM, Pedrosa ...
  • نمایش کامل مراجع