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CRISPR/Cas mediated genome editing in medicinal plants

Year: 1399
COI: MPSA11_049
Language: EnglishView: 198
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Rahim Ghezzi - Master student in plant genetics and breeding
Leila Nejad Sadeghi - Assistant Professor, Department of Plant Production Engineering and Genetics, Faculty of Agriculture, Shahid Chamran University of Ahvaz.


The safe application of the organic materials leads to more popularity of plant-derived medicines in the recent years. For a long time, classical biotechnology techniques have been exploited in order to obtain a multitude of beneficial traits like, from unraveling the entire metabolic pathwayto increased metabolite and nutrient production, etc. However, conventional genetic engineering methods are not suitable for adding large-concerted changes into a plant, because the random insertion of DNA construct into one or more loci in one or more chromosomes can lead toundesirable effects. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins) system was first identified in bacteria and archaea and candegrade exogenous substrates. Therefore, CRISPR/Cas is considered a revolutionary technology in plant biology. Here, we introduce the mechanism of the CRISPR/Cas in particular CRISPR/Cas9, update its recent advances in various applications in plants, and discuss its future prospects to provide an argument for its use in the study of medicinal plants.


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Ghezzi, Rahim and Nejad Sadeghi, Leila,1399,CRISPR/Cas mediated genome editing in medicinal plants,11th National Conference on Medicinal Plants and Sustainable Agriculture,Hamadan,

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