افسانه کرمی - Infectious Disease Ward, Vali-e-Asr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
سعیده مظلوم زاده - School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
منیژه جزه پناهی - Infectious Disease Ward, Vali-e-Asr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
میترا فرشیدفر - Zanjan University of Medical Sciences, Zanjan, Iran

Background and Objective: Streptococcal pharyngitis is one of the most common bacterial infections that its improper treatment could lead to complications such as heart and kidney problems. Although streptococcal pharyngitis makes up a low percentage of pharyngitis etiology, penicillin derivatives are prescribed for many of the patients with pharyngitis. The aim of this study was to determine the prevalence of streptococcal infection in pharyngitis patients treated with penicillin derivatives as well as their drug resistance patterns. Materials and Methods: This cross-sectional trial was performed on ۴۳۷ patients aged between ۱-۹۰ years with pharyngitis admitted to the emergency ward and treated with penicillin derivatives. A throat swab for culture and smear preparation for group A beta hemolytic streptococus was done for each patient, followed by evaluation of antibiotic resistance to group A hemolytic streptococci. Results: From a total of ۴۳۷ patients diagnosed with streptoccocal pharyngitis, only ۳۱ patients (۷.۰۹%) turned up positive for group A beta hemolytic streptococci. Drug resistancy to Erythromycin ۳۸.۲%, Gentamicin ۵۸.۸% and Penicillin ۲.۹% were reported. Conclusion: Considering the fact that ۷.۰۹% of the patients required antibiotic therapy, the irrational consumption of antibiotics likely leads to an increased likelihood of drug resistance or allergy. This issue deserves special attention in the continuing educational programs for physicians.

Keywords: Antibiotic resistancy, Pharyngitis, Penicillin derivatives, Streptococci