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Title

Seroprevalence of Cytomegalovirus Antibodies by Electrochemiluminescence Method in Young Women Referred to the Clinical Laboratory, Sanandaj, Iran

Year: 1399
COI: JR_INJER-7-2_008
Language: EnglishView: 70
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Authors

Mazaher Khodabandehloo - Ph.D, Cellular and Molecular Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran
Pezhman Sharifi - M.Sc, Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran

Abstract:

   Background and aims: Maternal primary and recurrent infection of cytomegalovirus (CMV) may be transmitted to the fetus during pregnancy and may have complications such as death or growth, along with the development retardation of the fetus and infant. The aim of this study was to determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies against CMV in young women, Sanandaj, Iran. Methods: To this end, ۹۰ women (۱۵-۴۰ years old) referring to a clinical laboratory were randomly selected and announced their informed consent to participate in this cross-sectional study. Demographic information and women’s data were collected, including pregnancy, history of abortion, and history of blood transfusion. Then, women’s sera were measured for CMV IgG and IgM antibodies using the electrochemiluminescence technique. Finally, the data were analyzed by SPSS statistical software. Results: The prevalence of IgG and IgM antibodies against CMV in women was ۹۲.۲% (۹۵% CI = ۸۶.۵-۹۷.۸) and ۰%, respectively. In addition, the average CMV IgG antibody level was about ۱۳۷.۵۲ ± ۸۵.۲۱۵ SD IU/mL. The results revealed a significant statistical association between IgG antibody and pregnancy (P value = ۰.۰۱۲) while there was no association between CMV IgG antibody and other demographic data. Conclusions: In general, high percentages of women had CMV IgG antibody whereas ۷.۸% of them were susceptible. They are expected to acquire CMV primary infection, and therefore, the screening of antibodies to CMV is suggested for prenatal care.

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This Paper COI Code is JR_INJER-7-2_008. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1223008/

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Khodabandehloo, Mazaher and Sharifi, Pezhman,1399,Seroprevalence of Cytomegalovirus Antibodies by Electrochemiluminescence Method in Young Women Referred to the Clinical Laboratory, Sanandaj, Iran,https://civilica.com/doc/1223008

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Type of center: دانشگاه دولتی
Paper count: 6,311
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