Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها
Paper
Title

Uncoupling Protein ۲ Expression Modulates Obesity in Chronic Kidney Disease Patients

Year: 1400
COI: JR_RBMB-10-1_013
Language: EnglishView: 65
This Paper With 7 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 7 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:

Authors

Salma Ahmed Shawky - Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Osama Gaber - Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Ezzat Mostafa - Internal Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Walaa Mohamed Sarhan - Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Abstract:

Background: Obesity is a multifactorial metabolic disease resulting from behavioral and genetic factors. Obesity is linked to diabetes mellitus and hypertension, which are considered as major risk factors for chronic kidney disease (CKD); moreover, it has a direct effect on developing CKD and end stage renal disease (ESRD). Here was aimed to examine the association between uncoupling protein ۲ (UCP۲) gene expression and obesity in CKD patients. Methods: UCP۲ gene expression was analyzed by real time polymerase chain reaction (RT-PCR) in ۹۳ participants divided into three groups. The groups included ۳۱ non-obese CKD patients, ۳۱ obese CKD patients, and ۳۱ healthy, age-matched, unrelated volunteers as a control group. Results: UCP۲ gene expression was significantly relevant when comparing the non-obese CKD and obese CKD groups to the control group (p< ۰.۰۰۱). No significant association was found when the groups were compared by gender; Chi-square (X۲) was ۲.۳۸ and p= ۰.۳۰۴. A significant negative correlation was found between UCP۲ gene expression and BMI in CKD (p< ۰.۰۵). Conclusions: These results indicate that UCP۲ gene expression plays a significant role as a risk factor for obesity in CKD patients.

Keywords:

Chronic kidney disease (CKD) , obesity , Uncoupling protein ۲ (UCP۲) gene expression , Real-Time polymerase chain reaction (RT-PCR)

Paper COI Code

This Paper COI Code is JR_RBMB-10-1_013. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1225397/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Shawky, Salma Ahmed and Gaber, Osama and Mostafa, Ezzat and Sarhan, Walaa Mohamed,1400,Uncoupling Protein ۲ Expression Modulates Obesity in Chronic Kidney Disease Patients,https://civilica.com/doc/1225397

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :

  • Remuzzi G, Benigni A, Remuzzi A. Mechanisms of progression and ...
  • GBD ۲۰۱۵ DALYs and HALE Collaborators. Global, regional, and national ...
  • Couser WG, Remuzzi G, Mendis S, Tonelli M. The contribution ...
  • Obesity and overweight. World Health Organization. ۲۰۱۵ ...
  • Glasgow RE, Terborg JR, Hollis JF, Severson HH, Boles SM. ...
  • Singh GM, Danaei G, Farzadfar F, Stevens GA, Woodward M, ...
  • Czernichow S, Kengne AP, Stamatakis E, Hamer M, Batty D. ...
  • Lauby-Secretan B, Scoccianti C, Loomis D, Grosse Y, Bianchini F, ...
  • Anandacoomarasamy A, Caterson I, Sambrook P, Fransen M, March L. ...
  • Anstey KJ, Cherbuin N, Budge M, Young J. Body mass ...
  • Mathew AV, Okada S, and Sharma K. Obesity related kidney ...
  • Othman M, Kawar B, El Nahas AM. Influence of obesity ...
  • Hsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS. ...
  • Dutra MRH, Feliciano RDS, Jacinto KR, Gouveia TLF, Brigidio E, ...
  • Gimeno RE, Dembski M, Weng X, Deng N, Shyjan AW, ...
  • https://doi.org/۱۰.۲۳۳۷/diabetes.۴۶.۵.۹۰۰Rubattu S, Cotugno M, Bianchi F, Sironi L, Gelosa P, ...
  • Arsenijevic D, Onuma H, Pecqueur C, Raimbault S, BS Manning, ...
  • Mattiasson G, and Sullivan PG, (۲۰۰۶). The emerging functions of ...
  • Surniyantoro HNE, Sadewa AH, Hastuti P. Uncoupling protein ۲ (UCP۲) ...
  • Ng M, Fleming T, Robinson M, Thomson B, Graetz N, ...
  • Ladabaum U, Mannalithara A, Myer PA, Singh G. Obesity, abdominal ...
  • Bhargava P, Schnellmann RG. Mitochondrial energetics in the kidney. Nat ...
  • Rousset S, Alves-Guerra MC, Mozo J, Miroux B, Cassard-Doulcier AM, ...
  • Kovesdy CP, Furth S, Zoccali C. Obesity and kidney disease: ...
  • Ikizler TA. Resolved: being fat is good for dialysis patients: ...
  • Stenvinkel P, Lindholm B. Resolved: being fat is good for ...
  • Tomaszewski M, Charchar FJ, Maric C, J McClure, L Crawford, ...
  • Oberkofler H, Dallinger G, Liu YM, Hell E, Krempler F, ...
  • Sujata RM, Lele RD, Saranath D, Seth A, Parikh V. ...
  • Nordfors L, Hoffstedt J, Nyberg B, Thörne A, Arner P, ...
  • Brandao CFC, Carvalho FGD, Nicoletti CF, Junqueira-Franco MVM, Couto-Lima CA, ...
  • Oliveira M, Rheinheimer J, Moehlecke M, Rodriguesa M, Assmannab TS, ...
  • Millet L, Vidal H, Andreelli F, Larrouy D, Riou JP, ...
  • Simoneau, JA, Kelley DE, Neverova M, Warden CH. Overexpression of ...

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.

Support