Keihan Ghatreh Samani - Clinical Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran
Effat Farrokhi - Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran
Neda Mohandes Samani - Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran
Hadiseh Hadiseh Moradi - Student of Medicine, Shahrekord University of Medical Sciences, Shahrekord, I.R. Iran

Background and aims: The aluminum-containing compounds are used as glaze in tile and ceramic production plants. It means that the workers working in these plants are in direct exposure to aluminum-containing compounds. The aim of this study was to assess the potential damages caused by aluminum among tile plant workers. Methods: In this cross-sectional study, ۶۰ workers whom were in direct exposure to glazing material were enrolled as case group and ۱۱۲ workers whose jobs were different from the case group and who had no exposure to the chemical materials in tile plants were considered as control group. After taking fasting blood samples, it was performed cell count tests using an automated blood cell counter. Serum iron and liver function test were measured using auto analyzer. Serum aluminum measurement was done by graphite furnace atomic absorption spectrometry and ferritin was measured by ELISA. Results: The serum aluminum level was significantly higher in the case group (۷.۲۶±۲.۶۳) than the control group (۵.۴۸±۱.۷۵) (P<۰.۰۰۱), as well as the mean hemoglobin level was lower in the case group (۱۴.۲۸±۰.۸۸) than the control group (۱۵.۴۴±۱.۱۹) (P<۰.۰۱۱). However, the mean level of iron and ferritin as well as liver tests exhibited no significant difference between two groups (P>۰.۰۵). Conclusion: Occupational exposure to aluminum in tile production industries could increase the serum aluminum level but may decrease blood hemoglobin concentration, which is a predisposing factor for anemia possibly through intervening in blood iron and ferritin.

Aluminum, ferritin, Iron, Tile glazing, Anemia