Lobular Carcinoma of Breast Presenting with Skin and Stomach Metastases

Background: Skin metastases occur in ۱-۵% of solid tumors and are rarely thepresenting sign of internal malignancies. Certain features in skin lesions raisesuspicion of metastasis from solid tumors.Case Presentation: In this article a ۶۱-year-old woman is presented witherythematous skin nodules in upper abdomen and chest. Histopathologicalevaluation of lesions suggested metastatic carcinoma and a thorough search foundstomach signet cell adenocarcinoma and breast lobular carcinoma.Immunohistochemical staining confirmed diagnosis of lobular carcinoma withmetastasis developed in skin and stomach.Conclusion: Clinicians must be aware that malignancies can present by skinmetastases. Since breast and stomach cancer can both metastasize to skin,immunohistochemistry evaluation is of great importance to diagnose the primary tumor.

Keywords:

breast cancer , skin metastasis , Lobular carcinoma , stomach metastasis , Immunohistochemistry