A computational method to analyze the similarity of biological sequences under uncertainty

In this paper, we propose a new method to analyze the difference and similarity of biological sequences, based on the fuzzy sets theory. Considering the sequence order and some chemical and structural properties, we present a computational method to cluster the biological sequences. By some examples, we show that the new method is relatively easy and we are able to compare the sequences of arbitrary lengths.

Keywords:

Similarity of biological sequences , Fuzzy polynucleotide space , Fuzzy clustering , Unit hypercube , Fuzzy similarity matrix