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Paper
Title

Using self-assembling peptide Nano-fiber in regenerative medicine

Year: 1399
COI: NANOB03_027
Language: EnglishView: 32
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Authors

Sadra Amir pour haradasht - DDS student _ Dental Students Scientific Research Center (DSSRC) association of forensic dentistry _ Tehran University of Medical Sciences

Abstract:

Nanotechnology will be the foundation of many science and technologies in the ۲۱st century. The role of regenerative medicine has been recently increased due to developments of bio-nanothechnology. One of the most interesting Biomaterials made in this field of science is self-assembling peptide Nanofibers. The formation of a specific conformation of one protein is owing to the self-assembling of it s amino acids. So, researchers can design self-assembly of peptides at the molecular and Nano molecular level and can control It s formation and configuration. Peptide Nano fibers are used to make a scaffold for tissue regeneration and are gaining interest in tissue engineering programs. They can self-organize their structures from basic building blocks to supramolecular structures. Nowadays, more emphasis is placed on Bio-functionalization strategies to influence cell behavior and modulate scaffold stability. To synthesize peptides and their hybrid structures, there are three main methods: solid-phase chemical synthesis, protein engineering, and ring-opening polymerization strategy. There are two main groups of self-assembling nano-structures : ۱.Linear peptide monomers like amphiphilic peptides, ionic-complementary peptides, etc ۲.Non linear peptide monomers like yclic peptides and hybrid peptides. Regenerative medicine and tissue engineering using Nano structural scaffolds for the regrowth of nerve cells has been demonstrated in Vivo. Self-assembling peptides for in Vitro applications and ۳D culture as well as in Vivo for tissue regeneration such as bone and optic nerve repair, like for drug delivery of mediators is improving a new generation of therapy.Methods and Materials:A search was conducted using the databases such as Medline or PubMed and Google Scholar for articles from ۲۰۱۰ to ۲۰۱۸. The selected key words were Regenerative medicine, self-assembling nanofibers, Biomaterial. This article provides a summary of the findings from studies that present use of self-assembling peptide Nano-fiber in regenerative medicine .

Keywords:

Paper COI Code

This Paper COI Code is NANOB03_027. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1235572/

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If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Amir pour haradasht, Sadra,1399,Using self-assembling peptide Nano-fiber in regenerative medicine,Third International Conference on Interdisciplinary Studies in Nanotechnology,Tehran,https://civilica.com/doc/1235572

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Type of center: علوم پزشکی
Paper count: 7,707
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