The effect of topical endometrial scratching on pregnancy outcome in women with previous failure of intrauterine insemination: A non-randomized clinical trial

Background: The prevalence of infertility is increasing worldwide and the treatment is one of the important issues. Objective: This study aimed to evaluate the effect of local endometrial scratching on pregnancy outcomes in women with previous failure of intrauterine insemination. Materials and Methods: This non-randomized clinical trial study was performed on ۳۳۶ women referred to the infertility clinic of Ali ebn-e Abitaleb Hospital of Zahedan (between May and November ۲۰۱۹). Women were divided into two groups: endometrial scratch as case and control group. In the case group (n = ۱۷۳), endometrial scratching was performed on day ۸-۹ of the menstrual cycle in addition to routine infertility treatments, while in the control group (n = ۱۶۳), only routine treatment was performed. Chi-square test was used to compare the frequency of male factor severity and the percentage of successful pregnancies between both groups and was used to investigate the effect of male factor on the fertility rate in each group (moderate male factor and mild male factor). Results: The mean age of the women was ۲۸.۴ ± ۵.۲ yr. The success rate of pregnancy in the case group was ۱۲.۳% and in the control group ۱۱%, which were not statistically significant (p = ۰.۶۹۷). Conclusion: Overall, the results of this study showed that endometrial scratching had no effect on the pregnancy rate.

Keywords:

Infertility , Endometrial , Scratch , Insemination. , ناباروری , خراش آندومتریال , IUI.