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Title

Effects of physical activity and obesity on hypertension: A narrative mini-review of the main effective mechanisms

Year: 1400
COI: JR_JCTM-9-2_001
Language: EnglishView: 54
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Authors

Saleh Rahmati-Ahmadabad - Department of Physical Education, Pardis Branch, Islamic Azad University, Pardis, Iran.
Fahimeh Hosseini - Exercise Biochemistry Division, Faculty of Sport Sciences, University of Mazandaran, Babolsar, Mazandaran, Iran
Amir Khalaj - Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Kiarash Faiz Mahdavi - Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Mahmood Omrani - Department of Physical Education, Pardis Branch, Islamic Azad University, Pardis, Iran.

Abstract:

Physical activity (PA) and obesity are effective interventions for hypertension. The current study is a review to explain possible mechanisms related to the effects of PA and obesity on hypertension. To this end, several scientific databases were searched using the keyword "hypertension" and also some English articles related to obesity and PA were investigated. Then, the mechanisms of obesity and PA associated with hypertension were extracted from the collected articles. Overall, obesity causes an increase in renin-angiotensin-aldosterone (RAA) systems, harmful changes in lipid and lipoprotein profile, a decrease in insulin sensitivity, as well as harmful changes in adipokines, oxidative stress, and inflammatory factors. PA improves the above-mentioned changes caused by obesity. Overall, PA mainly via an effect on oxidative stress, inflammation, endothelial cells, the elasticity of arteries, body weight, the activity of the RAA system, activity of parasympathetic and renal function as well as improve the insulin sensitivity has positive effects on hypertension. It should be noted that the effects of PA against hypertension is highly variable and they are related to PA modes, environmental and genetic factors.

Keywords:

Adipokines , Insulin sensitivity , lipid and lipoprotein profile , Oxidative Stress Renin-Angiotensin-Aldosterone Systems

Paper COI Code

This Paper COI Code is JR_JCTM-9-2_001. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1240603/

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Rahmati-Ahmadabad, Saleh and Hosseini, Fahimeh and Khalaj, Amir and Faiz Mahdavi, Kiarash and Omrani, Mahmood,1400,Effects of physical activity and obesity on hypertension: A narrative mini-review of the main effective mechanisms,https://civilica.com/doc/1240603

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    Type of center: Azad University
    Paper count: 1,296
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