The Incidence of Ovarian Involvement in Endometrioid Endometrial Adenocarcinoma: A Retrospective Analysis

Background & Objective: Endometrial carcinoma is the most common malignancy of the female genital tract, which most often affects postmenopausal women. The ovaries may be active when a patient has endometrial cancer, so removing an ovary can worsen a patientchr('۳۹')s quality of life. On the other hand, a complete surgical staging in endometrial cancer includes oophorectomy since ۱۹۸۸. There has been some research to assess whether an oophorectomy should be performed and in which cases, ovaries can be preserved. Materials & Methods: Aim of this study was to evaluate the coexistence of ovarian involvement in endometrioid endometrial carcinoma. In this study, we evaluated ۱۸۰ patients with endometrioid endometrial cancer patients who were surgically staged at Imam Hossein Hospital between ۲۰۰۴ and ۲۰۱۷. Results: Mean age of subjects of the study was ۵۶.۷۸ ±۱۰.۵۹. Forty-six of patients (۲۵.۶ %) were less than ۵۰ years old and ۷۴.۴ % (۱۳۴) were older than ۵۰. Twenty out of ۱۸۰ (۱۱.۱ %) of them had ovarian involvement (one of them had simultaneous ovarian tumor) and ۱۱ (۵۵%) of these cases were less than ۵۰ years old. In ۵۵ % (۱۱) patients, the involved ovaries were less than ۵ cm with grossly normal appearance, lymph nodes metastases were detected in ۳ out of ۲۰ (۱۵ %) of them although their ovarian size were ۴, ۴.۵ and ۶.۵ cm. In ۱۰ (۵۰ %) of them, deep myometrial invasion was detected. Conclusion: In endometrial cancer staging, ovarian preservation could be a challenging decision and a real controversy which needs more researches.

Keywords:

Endometrial cancer , Ovarian cancer , Ovarian metastasis , Synchronous ovarian cancer