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Title

The Frequency of Cytomegalovirus and Toxoplasma Among Microcephalic and Hydrocephalic Neonates Admitted to Pediatric Hospital in Bandar Abbas

Year: 1399
COI: JR_IEJM-9-2_003
Language: EnglishView: 86
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Authors

Maryam Rostamian - Student Research Committee, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Seyyed Hossein Saadat - Pediatric Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Mohammad Mehdi Mashayekhi - Student Research Committee, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Hosein Hamadiyan - Student Research Committee, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Mehran Ahmadi - Pediatric Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Abstract:

Background: Congenital infection is a primary cause of malformations during infancy including hydrocephaly and microcephaly. In addition, cytomegalovirus and toxoplasma are the two prevalent causes of congenital infections. The present research aimed to investigate the prevalence of cytomegalovirus and toxoplasma infections among neonates afflicted with microcephaly and hydrocephaly in a pediatric hospital in ۲۰۱۸.Materials and Methods: The present descriptive, cross-sectional research was conducted on all neonates diagnosed with microcephaly and hydrocephaly hospitalized in the pediatric hospital of Bandar Abbas in ۲۰۱۸. Blood samples were taken from the neonates to be analyzed for cytomegalovirus and toxoplasma serology, followed by statistically analyzing the information describing ۱۱ subjects including ۵ hydrocephaly and ۶ microcephaly cases.Results: The mean gestational age was estimated at ۳۵.۸ ± ۴.۰۸ and ۳۷.۱۶ ± ۱.۳۲ weeks in hydrocephaly and microcephaly groups, respectively (P = ۰.۵۰۷). In both groups, the female population was larger than the males. In addition, blood relations among parents were stronger in the microcephaly group (۴۰%) compared to the microcephaly group (۸۳.۳%). Moreover, the anomaly was found to be more in the microcephaly group. This rate was ۶۰% and ۱۶.۷% in the hydrocephaly and microcephaly groups, respectively. The serology of cytomegalovirus and toxoplasma in neither groups showed to be positive. One hundred percent of patients with an anomaly were term although ۵۰% of those without any anomaly belonged to the term group. It appears that the presence of an anomaly was positively correlated with term birth. One hundred percent of patients with an anomaly were found to have parents who were close relatives. However, ۵۰% of patients with no anomaly showed to have parents closely related in the family. Finally, heart problems were found to prevail in the group diagnosed with an anomaly.Conclusion: In the present research, the prevalence of cytomegalovirus and toxoplasma infections was reported to be zero in neonates who were afflicted with microcephaly and hydrocephaly.

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This Paper COI Code is JR_IEJM-9-2_003. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1243379/

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Rostamian, Maryam and Saadat, Seyyed Hossein and Mashayekhi, Mohammad Mehdi and Hamadiyan, Hosein and Ahmadi, Mehran,1399,The Frequency of Cytomegalovirus and Toxoplasma Among Microcephalic and Hydrocephalic Neonates Admitted to Pediatric Hospital in Bandar Abbas,https://civilica.com/doc/1243379

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Type of center: علوم پزشکی
Paper count: 834
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