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Title

Manifestly Altered MicroRNAs in Poly Cystic Ovary Syndrome

Year: 1399
COI: JR_IEJM-9-2_004
Language: EnglishView: 87
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Authors

Mahta Moraghebi - Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Milad Rafat - Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Pegah Mousavi - Department of Medical Genetics, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Kianoosh Malekzadeh - Department of Medical Genetics, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Abstract:

MicroRNAs (miRNAs) constitute a large family of small non-coding RNAs which regulate gene expression at the surface following transcription. They are widely involved in many physiological and pathological processes including polycystic ovarian syndrome (PCOS). PCOS is an endocrine disorder in women. Currently, there is no comprehensive information about the role of miRNAs in PCOS. Thus, this paper has attempted to collate studies on miRNAs in order to determine important changes in their miRNA expression profile in the total blood, serum, plasma, follicular fluid, and granulosa cells in PCOS patients alongside the genes which are targeted for regulation by these miRNAs. This study presents a new approach for using miRNAs and their target genes for diagnosing and treating PCOS.

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This Paper COI Code is JR_IEJM-9-2_004. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1243380/

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Moraghebi, Mahta and Rafat, Milad and Mousavi, Pegah and Malekzadeh, Kianoosh,1399,Manifestly Altered MicroRNAs in Poly Cystic Ovary Syndrome,https://civilica.com/doc/1243380

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Type of center: علوم پزشکی
Paper count: 834
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