Seroepidemiological Prevalence of Human Brucellosis in Gorgan and Dasht, Iran

Background: Brucellosis is an important zoonotic disease with significant economic and public health consequences. This study aimed to investigate the seroepidemiological prevalence of human brucellosis in Gorgan and Dasht, Northeastern Iran during one year. Materials & Methods: In this study, ۱۵۳ brucellosis-suspected cases who were referred to the health centers of Gorgan and surrounding villages from April ۲۰۱۷ to March ۲۰۱۸, were included. Two serological assays (Wright and ۲-mercaptoethanol) were performed on all sera taken from patients. Data were analyzed by SPSS software (version ۲۳) using Chi-square test and independent t-test. A p-value less than .۰۵ was considered as statistically significant. Findings: Of ۱۵۳ suspected cases, ۶۲ cases (۴۰.۵%) were positive for brucellosis, among whom ۳۹ cases (۶۲.۹%) were men, and ۴۱ cases (۶۶%) were ۱۷-۳۸ years old. The highest prevalence rate of brucellosis was observed in rural men (۶۹.۵%) as well as in those consuming raw cheese (۳۵.۵%) and being in direct contact with livestock (۲۷.۵%). Furthermore, the frequency of the disease was significantly higher in the summer. The incidence rate of the disease was significantly associated with season, history of contact with livestock, and the type of dairy product consumed (p <.۰۵). Conclusion: The prevalence of brucellosis is higher in rural areas of Gorgan, particularly among farmers and livestock keepers. Providing training and raising awareness of these individuals as well as developing strategic health plans regarding the consumption of unpasteurized dairy products could help reduce the incidence of brucellosis.  

Keywords:

Brucellosis , Epidemiology , Serology