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Paper
Title

Investigation of Antimicrobial Effect of Ziziphus jujube on nosocomial bacterial infections

Year: 1399
COI: MEDISM21_216
Language: EnglishView: 35
نسخه کامل این Paper ارائه نشده است و در دسترس نمی باشد

Authors

Sheyda Jabbari - Department of biotechnology, Faculty of Science and Technology, Shahid ashrafi esfahani University, Isfahan, Iran
Maryam Sadat Mirbagheri Firoozabad - Department of Biology, Faculty of Science, Yazd University, Yazd, Iran

Abstract:

Background and Aim : The Incidence of drug resistance against chemical antimicrobial drugs has led to attention to the use of medicinal plants in the treatment of infections. The aim of this study was to evaluate the antimicrobial activity of extracts of Ziziphus jujube against pathogenic bacteria especially nosocomial infections.Methods : In this experimental study, aqueous and alcoholic extracts of, Ziziphus jujube were extracted. Inhibitory effects of plant extracts against Pathogenic bacteria (Staphylococcus saprophyticus, Escherichia coli, Salmonella typhimurium and Proteus mirabilis) and Pathogenic nosocomial (Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter and Pseudomonas aeruginosa) Through Disk diffusion methods, well diffusion method, and microdilution were investigated. Serial dilutions of the extracts were prepared in the range of ۵۰ to ۱۰۰۰ mg / ml to determine the minimum inhibitory concentration.Results : The aqueous extract of the plant showed higher inhibitory effects against microbial strains than the alcoholic extract. The two strains of Staphylococcus saprophyticus and Staphylococcus aureus showed greater sensitivity than extracts (aqueous, methanol, ethanol). Statistically, there was a significant difference in the minimum inhibitory concentration of aqueous extract growth compared to alcoholic extracts The aqueous extract on gram-positive bacteria of Staphylococcus saprophyticus and Staphylococcus aureus had a minimum inhibitory concentration of ۱۳۳ mg / ml and a minimum bacteriocidal concentration of ۲۰۰ mg / ml.Conclusion : The study found that Ziziphus jujube extract had significant effects on microorganisms, inhibitory zone of two gram positive bacteria including , Staphylococcus saprophyticus, ۵۷ mm in diameter, Staphylococcus aureus, ۵۵ mm in diameter, And the bacterium Pseudomonas aeruginosa showed the highest resistance between gram-negatives bacteria. The extracts also showed significant effects compared to the antibiotics as contorol. Although further research is needed in this regard, Ziziphus jujube extract can be suggested as a new antimicrobial agent in medicine resarch.

Keywords:

Medicinal plant extract , Pathogenic bacteria , MIC Minimum Inhibitory Concentration , Digestive and skin diseases

Paper COI Code

This Paper COI Code is MEDISM21_216. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1254892/

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If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Jabbari, Sheyda and Mirbagheri Firoozabad, Maryam Sadat,1399,Investigation of Antimicrobial Effect of Ziziphus jujube on nosocomial bacterial infections,21th International Congress of Microbiology of Iran,Tehran,https://civilica.com/doc/1254892

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Type of center: موسسه غیرانتفاعی
Paper count: 537
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