A systematic Review about Clinical features and computed tomography findings of COVID-۱۹ Positive Patients

Background and Aim : Novel coronavirus is pandemic public health that it has begun from December ۲۰۱۹ in city Wuhan, China. The aim of this study was to determine the most common clinical features and Computed tomography findings among patients infected by COVID-۱۹.Methods : We have used different databases such as ISC, science direct, Embase (Elsevier), Web of Science, Scopus and Medline via PubMed. Searches were performed by key words including: ۲۰۱۹-nCoV, SARS-CoV-۲, ۲۰۱۹ novel coronavirus, COVID-۱۹ virus, coronavirus disease ۲۰۱۹ virus, Wuhan coronavirus, clinical presentation, clinical syndromes, clinical characterization, clinical symptoms, clinical signs, clinical feature, imaging finding, computed tomography (CT) feature, lung CT scan, pulmonary CT scan and chest CT scan.Results : A total number of ۱۰۴۷ articles were found collectively amongst the databases. As the title screening was performed, ۴۹۲ articles were removed. Abstract screening resulted in ۳۰۶ more studies to be omitted during the search. Finally, after full text screening, ۴۲ articles remained (See figure۱). ۴۲ articles reported clinical feature, ۵ of publications were abstract because full texts written in Chinese among them ۲۵ articles reported chest CT finding of COVID ۱۹ patient. The most frequent signs COVID-۱۹ disease were pointed fever and cough in all of studies. Among ۴۲ studies were used: ۳۴ (۸۰.۹%), ۲۹ (۶۹.۰۴%), ۲۴(۵۷.۱%) and ۱۹(۴۵.۲%) were reported fatigue, diarrhea, headache, dyspnea and expectoration as common symptoms respectively. Other sign included: sore throat, shortness of breath, nasal discharge, hemoptysis and chill. In chest CT scan finding, ۲۰(۸۰%) of studies were introduced ground glass opacity and ۱۹(۷۶%) bilateral involvement as the most common patterns. Then ۱۴(۵۶%) and ۱۱(۴۴%) of publication were mentioned consolidation and unilateral pneumonia respectively. Chest CT morphology were crazy paving, halo sing, vascular enlargement, reticulation, tree in bud, plural effusion, air broncho gram and nodule.Conclusion : Know of common clinical feature and chest CT scan due to early identification of COVID-۱۹ positive patients and prevention of transmission among humans is very important.

Keywords:

COVID-۱۹ , Clinical Characteristics , Cough , Fever , CT Finding , Ground Glass Opacity