Publisher of Iranian Journals and Conference Proceedings

Please waite ..
Publisher of Iranian Journals and Conference Proceedings
Login |Register |Help |عضویت کتابخانه ها
Paper
Title

An In vitro Study on Curcumin Delivery by Nano-Micelles for Esophageal Squamous Cell Carcinoma (KYSE-۳۰)

مجله گزارش های بیوشیمی و زیست شناسی مولکولی، دوره: 6، شماره: 2
Year: 1397
COI: JR_RBMB-6-2_004
Language: EnglishView: 71
This Paper With 7 Page And PDF Format Ready To Download

Buy and Download

با استفاده از پرداخت اینترنتی بسیار سریع و ساده می توانید اصل این Paper را که دارای 7 صفحه است به صورت فایل PDF در اختیار داشته باشید.
آدرس ایمیل خود را در کادر زیر وارد نمایید:

Authors

Sare Hosseini - Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Jamshidkhan Chamani - Department of Biology, Faculty of Sciences, Islamic Azad University-Mashhad Branch, Mashhad, Iran.
Hamidreza Rahimi - Department of Modern Sciences & Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Navid Azmoodeh - Department of Biology, Faculty of Sciences, Islamic Azad University-Mashhad Branch, Mashhad, Iran.
Faezeh Ghasemi - Department of Biotechnology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
Porya Hassan Abadi - School of Medicine, University of Birmingham, Birmingham, UK.

Abstract:

Background: The incidence of esophageal squamous cell carcinoma (ESCC) is increasing, causing catastrophic health burdens on communities. Curcumin has shown promise as a therapeutic agent in the treatment of colon, colorectal, pancreatic, and esophageal cancers but it has very poor bioavailability. The application of nano-carriers as drug delivery systems increases curcuminchr('۳۹')s bioavailability. Cyclin D۱ is overexpressed in ESCC and curcumin may change its expression. Methods: In this study, the effect of SinaCurcumin®, a novel nano-micelle product containing ۸۰ mg curcumin, on the growth of KYSE-۳۰ cells and expression of cyclin D۱, was investigated. Paclitaxel and Carboplatin served as reference drugs. Results: Nano-curcumin increased cell cytotoxicity, decreased IC۵۰, and down-regulated of cyclin D۱. However, treatment of cells with nano-curcumin might result in multidrug resistance. Conclusions: Nano-curcumin suppressed proliferation of KYSE-۳۰ cells and expression of cyclin D۱ although its use in combination with other chemotherapeutic agents requires further testing.

Keywords:

Paper COI Code

This Paper COI Code is JR_RBMB-6-2_004. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/1263002/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
Hosseini, Sare and Chamani, Jamshidkhan and Rahimi, Hamidreza and Azmoodeh, Navid and Ghasemi, Faezeh and Hassan Abadi, Porya,1397,An In vitro Study on Curcumin Delivery by Nano-Micelles for Esophageal Squamous Cell Carcinoma (KYSE-۳۰),https://civilica.com/doc/1263002

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :

  • Dawsey SP, Tonui S, Parker RK, Fitzwater JW, Dawsey SM, ...
  • Bosetti C, Levi F, Ferlay J, Garavello W, Lucchini F, ...
  • Rafiemanesh H, Maleki F, Mohammadian-Hafshejani A, Salemi M, Salehiniya H. ...
  • Enzinger PC, Mayer RJ. Esophageal cancer. The New England journal ...
  • Lehrbach DM, Nita ME, Cecconello I, Clinical Genomics of Esophageal ...
  • Phukan RK, Ali MS, Chetia CK, Mahanta J. Betel nut ...
  • Lin DC, Du XL, Wang MR. Protein alterations in ESCC ...
  • Dey B, Raphael V, Khonglah Y, GiriLynrah K. Expression of ...
  • Chuengsamarn S, Rattanamongkolgul S, Phonrat B, Tungtrongchitr R, Jirawatnotai S. ...
  • Rahimi HR, Kazemi Oskuee R. Curcumin From Traditional Iranian Medicine ...
  • Sandur SK, Pandey MK, Sung B, Ahn KS, Murakami A, ...
  • Menon VP, Sudheer AR. Antioxidant and anti-inflammatory properties of curcumin. ...
  • Kunnumakkara AB, Diagaradjane P, Anand P, Harikumar KB, Deorukhkar A, ...
  • O'Sullivan-Coyne G, O'Sullivan GC, O'Donovan TR, Piwocka K, McKenna SL. ...
  • Sahu RP, Batra S, Srivastava SK. Activation of ATM/Chk۱ by ...
  • Sandur SK, Deorukhkar A, Pandey MK, Pabon AM, Shentu S, ...
  • Jutooru I, Chadalapaka G, Lei P, Safe S. Inhibition of ...
  • Zhao X, Chen Q, Li Y, Tang H, Liu W, ...
  • Kanai M, Yoshimura K, Asada M, Imaizumi A, Suzuki C, ...
  • Shankar TN, Shantha NV, Ramesh HP, Murthy IA, Murthy VS. ...
  • Sharma RA, Euden SA, Platton SL, Cooke DN, Shafayat A, ...
  • Lao CD, Ruffin MTt, Normolle D, Heath DD, Murray SI, ...
  • Dhillon N, Aggarwal BB, Newman RA, Wolff RA, Kunnumakkara AB, ...
  • Huang MT, Lou YR, Ma W, Newmark HL, Reuhl KR, ...
  • Li Y, Wo JM, Liu Q, Li X, Martin RC. ...
  • Rahimi HR, Nedaeinia R, Sepehri Shamloo A, Nikdoust S, Kazemi ...
  • Rahimi HR, Mohammadpour AH, Dastani M, Jaafari MR, Abnous K, ...
  • Mukhopadhyay A, Banerjee S, Stafford LJ, Xia C, Liu M, ...
  • Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, ...
  • Li L, Braiteh FS, Kurzrock R. Liposome-encapsulated curcumin: in vitro ...
  • Bhawana, Basniwal RK, Buttar HS, Jain VK, Jain N. Curcumin ...
  • Sasaki H, Sunagawa Y, Takahashi K, Imaizumi A, Fukuda H, ...
  • Milano F, Mari L, van de Luijtgaarden W, Parikh K, ...
  • Subramaniam D, Ponnurangam S, Ramamoorthy P, Standing D, Battafarano RJ, ...
  • Du B, Jiang L, Xia Q, Zhong L. Synergistic inhibitory ...
  • Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J, ...

Research Info Management

Certificate | Report | من نویسنده این مقاله هستم

اطلاعات استنادی این Paper را به نرم افزارهای مدیریت اطلاعات علمی و استنادی ارسال نمایید و در تحقیقات خود از آن استفاده نمایید.

Scientometrics

The specifications of the publisher center of this Paper are as follows:
Type of center: علوم پزشکی
Paper count: 8,070
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

Share this page

More information about COI

COI stands for "CIVILICA Object Identifier". COI is the unique code assigned to articles of Iranian conferences and journals when indexing on the CIVILICA citation database.

The COI is the national code of documents indexed in CIVILICA and is a unique and permanent code. it can always be cited and tracked and assumed as registration confirmation ID.

Support