Mohammad Mesgari - M.Sc. student, Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran,
Mansour Mashreghi - Professor, Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran
Maryam M. Matin - Professor, Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran
Elaheh K. Goharshadi - Professor, Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran

Bacterial cellulose (BC) and Xanthan gum (XG) are used as renewable polymers in various fields, such as food and biomedical industries due to their unique physical properties. Today, the improvement of BC using nanoparticles (NPs) to create a new matrix has been attracted many researchers. In this study, BC was produced using Komagataeibacter xylinus (BPR ۲۰۰۱). Also, cerium oxide (CeO۲) NPs were synthesized using a green method. The FTIR and XRD analyses were performed for characterization the BC and CeO۲ NPs. Then, BC/XG/CeO۲ nanocomposite was prepared by casting method. The results confirmed the formation of both of BC and CeO۲ NPs. Therefore, the cytotoxicity effect of BC/XG/CeO۲ nanocomposite against NIH/۳T۳ cell line was evaluated using MTT method. The results showed that this nanocomposite had no cytotoxicity and can be used as a safe and biocompatible matrix for various biotechnological applications

Bacterial Cellulose, Xanthan Gum, CeO۲ NPs, NIH/۳T۳ cell line