The first case of fatal mucormycosis in a patient with Covid ۱۹ in Ghaem Hospital of Mashhad

Background and Aim : Fungal infections are one of the most common infections, especially in susceptible and immunocompromised patients. In some cases, the concurrence of fungal infections such as mucormycosis with other infections such as COVID-۱۹ can disrupt the treatment and control of the infection.Methods : The patient was a ۷۰-year-old woman with underlying diabetes who was admitted to Ghaem Hospital in Mashhad due to COVID-۱۹. He had sinusitis at the beginning of hospitalization and the maxillary sinuses were rapidly expanding necrotic. The sinus tissue specimen was examined for routine mycological procedures.Results : The results of direct experiments are reported by observing broad mycelium without septate (non-septate hyphae), with a Rhizopus spp. colony. Despite timely treatment with amphotericin B and other supportive therapies during COVID-۱۹, the patient died after ۱۰ days due to disease progression.Conclusion : Mucormycosis is one of the deadly and acute infections that timely diagnosis and treatment with new antifungals can be effective in reducing mortality, especially among COVID-۱۹ patients.

Keywords:

Fungal infection , Mucormycosis , COVID-۱۹ , Mashhad